In 1992 Sekiguchi wrote, directed and produced WHEN MRS. HEGARTY COMES TO JAPAN, a very personal project for the filmmaker, since Mrs. Hegarty and her late husband had been her "second parents" when she went to Australia as a young student who knew little English. The documentary chronicled Mrs. Hegarty's three-week visit to Japan, when she lived with Sekiguchi's family, and the result is in an illuminating study of cross-cultural experience and exchange. WHEN MRS. HEGARTY COMES TO JAPAN won both the Jury Award and the Audience Award at the Amsterdam International Documentary Film Festival, among other film festival prizes.
From 1993 to 1998, Sekiguchi worked as a commissioning editor at NHK in Japan and later wrote and directed a series of TV documentaries, including Undelivered Letters from the Past: Last Words by Japanese Soldiers from the Pacific War (2003), Manchuria (2004) and Until Death Part Us: Alzheimer Story (2005).
Sekiguchi's newest film, FAT CHANCE (2008), is another very personal project for the filmmaker, who, fast approaching fifty and finding herself overweight at nearly 200 pounds, determines to lose weight in hopes of becoming healthier and happier. She decided to film her six-month struggle, figuring that public humiliation would be a strong incentive to succeed.
Sekiguchi is currently developing a feature-length documentary called The Roudenko File, on Japan's dark secret on biological research unit during WWII, and also recently won a script development award in Japan to write and direct her first feature film, A Tale of Two Countries, an epic story of Sino-Japanese relationship through children's eyes.